LifeDNA is not a medical provider. Our tests are intended for informational and wellness purposes only and do not diagnose, treat, cure, or prevent any disease or medical condition. Results may vary. Supplement and wellness recommendations are based on genetic data and should be discussed with a qualified health professional before implementation. These statements have not been evaluated by the Food and Drug Administration.

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| 4.6

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METHYLATION GENES TEST

Most tests cover 5 genes.

We cover all 13.

If you've been researching methylation testing, you already know why it matters. What most tests don't tell you is how much they leave out.

Other tests: $599 for 5 genes vs. LifeDNA from $299 for all 13

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Simple saliva sample | Results in 3 to 5 weeks | 0% APR financing available

Chosen by tens of thousands of customers

135+ personalized wellness insights

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– THE PROBLEM

Partial testing gives you partial answers.

Partial testing gives you partial answers.

Methylation isn't controlled by one gene. It's a network of interacting pathways. When a test analyzes only part of that network, results can point you in the wrong direction entirely.

Methylation isn't controlled by one gene. It's a network of interacting pathways. When a test analyzes only part of that network, results can point you in the wrong direction entirely.

01

Tests that stop at MTHFR

MTHFR is the starting point, not the full picture. Your energy, mood, detoxification, and neurotransmitter function depend on at least 12 other genes working alongside it.

02

Small panels miss critical pathways

MTHFR is the starting point, not the full picture. Your energy, mood, detoxification, and neurotransmitter function depend on at least 12 other genes working alongside it.

02

Small panels miss critical pathways

Tests covering only 5 genes skip MAO-A, CBS, and VDR. These genes affect neurotransmitter clearance, sulfur metabolism, and vitamin D receptor function. Those gaps matter.

03

Wrong supplements, wasted money

When recommendations come from incomplete data, they may not address your actual bottlenecks. Some people take methylated B12 for years without results because the issue was in a gene their test never checked.

04

More questions than answers

People most frustrated after methylation testing are those whose results returned almost nothing actionable. A test should give you clarity, not more uncertainty.

– SIDE BY SIDE

LifeDNA vs. Other Methylations Tests

Here's exactly what you get with LifeDNA that most methylation tests don't include, and what the price difference actually looks like.

LifeDNA

Other Tests

All 13

Total Genes Tested

Only 5

Methylation Genes Test

Reports on Nutrition, Supplements, Fitness

Sleep, Skincare, and Personality Reports

Personalized Wellness Optimizations

Online Results Portal

Free DNA Updates

$399 $349

$599

Price

– COVERAGE COMPARISON

Every gene we test. See what others miss.

Most methylation tests cover the first 5 genes on this list and stop there. The additional genes address pathways that are also critical to how your methylation system functions.

Methylation isn't controlled by one gene. It's a network of interacting pathways. When a test analyzes only part of that network, results can point you in the wrong direction entirely.

Every gene we test. See what others miss.

Most methylation tests cover the first 5 genes on this list and stop there. The additional genes address pathways that are also critical to how your methylation system functions.

LIFEDNA

OTHERS

GENE

MTHFR

Folate metabolism, methylation cycle

MTR

B12 utilization, homocysteine

MTRR

B12 recycling efficiency

COMT

Dopamine breakdown, stress response

AHCY

Homocysteine metabolism

ACAT

Cholesterol and lipid metabolism

WHERE MOST TESTS STOP

BHMT

Betaine pathway, liver methylation

CBS

Sulfur metabolism, detox pathways

MAO-A

Serotonin and dopamine breakdown

MAT1A

SAMe production, methylation fuel

MTHFD1

Folate metabolism backup pathway

NOS3

Nitric oxide, cardiovascular function

SHMT1

Serine-glycine conversion, cell health

VDR

Vitamin D receptor, immune fuction

TOTAL GENES COVERED

14 (covered in 13 genes reports)

5

Why those additional genes matter.

MAO-A

Sometimes called the "warrior gene", it is involved in the breaking down of serotonin, norepinephrine, and dopamine. This variant may be associated with emotional disturbances.

VDR

Studies have shown that individuals with VDR variant(s) may exhibit a decrease in normal vitamin D receptor function. It also regulates some metabolic pathways related to the immune response. Most tests never look at this.

CBS

Some variants can cause excessive levels of homocysteine. Some studies have shown high levels of homocysteine to be associated with poor cardiovascular well-being.

13 Methylation Genes Test

You save $50

$299

$349

Full methylation panel with everything you need to get started.

As low as $24.92/mo for 12 months at 0% APR

Get This Test

Methylation Genes Report (all 13 genes)

LifeDNA Test Kit (cheek swab, shipped to you)

Personalized online portal

Free test updates

13 Methylation Genes Test with Complete Wellness Analysis

You save $50

$349

$399

Methylation plus powerful tests on nutrition, vitamins, fitness, and more.

As low as $29.08/mo for 12 months at 0% APR

Get This Test

Methylation Genes Report (all 13 genes)

LifeDNA Test Kit

Nutrition 

Fitness 

Vitamins and Supplements

Wellness and Sleep

Personality and Cognition 

Skincare 

MOST COMPREHENSIVE

LifeDNA Diamond: All-In-One DNA Wellness Blueprint

You save $200 — biggest savings on any plan

$399

$599

Everything in Wellness, plus gut, aging, detoxification, and a 1-on-1 consultation.

As low as $33.25/mo for 12 months at 0% APR

Methylation Genes Report (all 13 genes)

LifeDNA Test Kit

Nutrition 

Fitness 

Vitamins and Supplements 

Wellness and Sleep

Personality and Cognition 

Skincare 

Gut Microbiome

Bacteroides, Lactobacillus, Bifidobacterium, 7 others

Aging

Cognitive decline, bone loss, muscle mass decline, and 9 others

Detoxification Genes

CA1, PON1, GSTIP1, and 10 others

1-on-1 Methylation Deep Dive

Get Diamond – $399

– CHOOSE YOUR TEST

Pick the plan that fits your goals.

All plans include the full 13-gene methylation panel, a DNA kit, and your personalized online test portal. Mother's Day savings applied automatically.

REAL CUSTOMERS

From the people who almost went elsewhere.

From the people who almost went elsewhere.

4.6

out of 5

Verified

Very detailed DNA test results and fantastic consultation!

"I've been hearing a lot about DNA tests lately thanks to Gary Brecka, but they charge $600. I went to LifeDNA and got an insane amount of detail and a 30-minute consult for less than half the price of 10X Health."

JF

Jeff Feller

Verified

Methylation Test Experience

"I was concerned at first with not going with 10X but now you will be the only ones I recommend. Thanks for a seamless experience and such a great nutritionist in Daniela."

DM

Deverl Maserang

Verified

My experience with working with LifeDNA...

I researched all the companies and found that LifeDNA had a comprehensive approach and the cost was about 35% - 45% less than most companies in the marketplace. Once I got my results I was shocked how simply supplementing for my gaps gave me my energy back."

TS

Team Sato at HomeSmart

Trustpilot Reviews

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